Ibuprofen synthesis
Let me preface this with saying, I am not a professional. I am a chemistry student and none of this was performed in the lab, these are just my suggestions and attempts to synthesis this molecule.
Ibuprofen final attempt |
So, this is my take on the professional ibuprofen synthesis. In the professional synthesis, an anhydride was reacted with hydrogen fluoride to give a ketone, which is then reduced. Next, the carboxyl group was added. I decided to take out a step by reacting hydrogen fluoride with ethanal to go straight to the alcohol.
Ibuprofen first attempt |
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